Ethosomes: A Novel Approach in Vesicular Drug Delivery Systems
نویسندگان
چکیده
Transdermal drug delivery is a dosage form that applied topically to the skin layer (epidermis) which helps deliver into before entering systemic circulation. Ethosomes are soft, and flexible vesicles in rapid absorption. have better pharmaceutical properties than conventional liposomes such as room temperature stability, improved compatibility with Stratum Corneum barrier. non-toxic nature can be used preparation of cosmeceutical it has absorption skin. The most common disadvantage ethosome might not cost-effective. ethosomal patches stick all types. mechanism ethosomes mainly occurred due increased lipid fluidity within cell membrane caused by ethanol ethosome. As result, permeability increased. prepared using cold method hot method. Ethosome consists various evaluation parameters includes studies, content interaction study between vesicle filter membrane. highly lipophilic drugs like minoxidil, testosome, CBD, other antibiotic drugs. widely application for formulation transport DNA gene expression hence delivering vaccines transdermal route. Additionally, this field allows regulation medication release vivo long-term safety analysis, providing effective treatment. Ethosomal preparations promising future bioactive substances via distribution. discovery derivatives was crucial breakthrough research. preferred because they non-irritant GIT tract avoid first-pass metabolism.
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ژورنال
عنوان ژورنال: Journal of pharmaceutical research international
سال: 2022
ISSN: ['2456-9119']
DOI: https://doi.org/10.9734/jpri/2022/v34i28b36036